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Huntsman International LLC
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Tissue Solutions
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Orient Bio Company
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BioCarta
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Institute for Clinical Pharmacodynamics
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Tissue Solutions
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Pfizer Inc
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Eppley Laboratory Inc
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Alphamed INC
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Ziaja Ltd
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Johns Hopkins HealthCare
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Gallus BioPharmaceuticals
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Image Search Results
Journal: PLoS Computational Biology
Article Title: Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells
doi: 10.1371/journal.pcbi.1001113
Figure Lengend Snippet: Pathways significant by over representation analysis with respect to platinum drug sensitivity.
Article Snippet:
Techniques: Activation Assay, Binding Assay
Journal: Clinical and Translational Science
Article Title: PF ‐04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo‐Controlled Study
doi: 10.1111/cts.12604
Figure Lengend Snippet: Percent change from baseline at day 29 in biomarkers with PF ‐04447943 25 mg twice daily. The percent changes from baseline to day 29 in adhesion, aggregates, microparticle, coagulation, and hematology biomarkers are depicted in the forest plot. Estimates and 95% confidence intervals are based on repeated measures model. Statistically significant ( P < 0.15 after multiplicity correction using Holm‐Bonferroni stepdown procedure) changes from baseline are indicated by an asterisk. CI, confidence interval; ICAM, intercellular adhesion molecule; MPA, monocyte‐platelet aggregates; NPA, neutrophil‐platelet aggregate; RBC, red blood cell; TAT, thrombin‐antithrombin; VCAM, vascular adhesion molecule.
Article Snippet: A panel of biomarkers preselected as those relevant to SCD included: a panel of soluble adhesion molecules (E‐selectin, P‐selectin, intracellular adhesion molecule, and vascular adhesion molecule (Myriad/RBM; Austin, TX), leukocyte‐platelet aggregates (neutrophil‐platelet and monocyte‐platelet aggregates; Center for Platelet Research Studies (CPRS); Boston, MA); MAC‐1 integrin expression on monocytes and neutrophils (CPRS); microparticles (endothelial‐, RBC‐, and platelet‐derived microparticles; CPRS), and
Techniques: Coagulation